Journal article
Phylogeographic, genomic, and meropenem susceptibility analysis of Burkholderia ubonensis
EP Price, DS Sarovich, JR Webb, CM Hall, SA Jaramillo, JW Sahl, M Kaestli, M Mayo, G Harrington, AL Baker, LC Sidak-Loftis, EW Settles, M Lummis, JM Schupp, JD Gillece, A Tuanyok, J Warner, JD Busch, P Keim, BJ Currie Show all
Plos Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2017
Abstract
The bacterium Burkholderia ubonensis is commonly co-isolated from environmental specimens harbouring the melioidosis pathogen, Burkholderia pseudomallei. B. ubonensis has been reported in northern Australia and Thailand but not North America, suggesting similar geographic distribution to B. pseudomallei. Unlike most other Burkholderia cepacia complex (Bcc) species, B. ubonensis is considered non-pathogenic, although its virulence potential has not been tested. Antibiotic resistance in B. ubonensis, particularly towards drugs used to treat the most severe B. pseudomallei infections, has also been poorly characterised. This study examined the population biology of B. ubonensis, and includes th..
View full abstractGrants
Awarded by National Science Foundation
Funding Acknowledgements
This study was made possible by funding from the Australian National Health and Medical Research Council (grant IDs 236216, 383504, 605820, 1046812 and 1098337; https://www.nhmrc.gov.au/), the US Department of Defense Chemical and Biological Defense Program through the Defense Threat Reduction Agency (grant ID HDTRA1-12-C-0066; www.dtra.mil/), the Australian Research Council (grant ID LP110100691; www.arc.gov.au/), the US Centers for Disease Control and Prevention (grant ID NU50CK000480; www.cdc.gov), and the Northern Territory government (grant IDs NTRIB06 and NTRIB09; https://nt.gov.au/). EPP is funded by a USC Research Fellowship (http://usc.edu.au/), DSS is funded by an Advance Queensland Fellowship (AQRF13016-17RD2; http://advance.qld.gov.au/) and MK is supported by a Swiss National Science Foundation fellowship (PBBSB-111156; http://www.snf.ch/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.